Is an a-receptor agonist that promotes widespread vasoconstriction. As a result of early reports of renal failure from norepinephrine, combined with a general decrease in enthusiasm for vasoconstrictor drugs, norepinephrine is no longer considered a first-line drug for the management of circulatory shock. In cases of hypotension refractory to dopamine, it can be added as a second agent. The administration of any vasoconstrictor agent carries a risk of hyp.

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